He was started on semaglutide (0.25mg per week x 4 weeks, then 0.5mg per week x 12 weeks, maintained at 1mg per week) which decreased the severity of his psoriasis and improved his quality of life
10.1016/j.biopha.2003.11.005 Tateishi N, Higashi T, Naruse A, Hikita K, Sakamoto Y: Relative contributions of sulfur atoms of dietary cysteine and methionine to rat liver glutathione and proteins
However, it is important to remember that GLP-1 medications are not a one-size-fits-all solution
Safety Monitoring Recommendations Based on the available clinical trial data, clinicians prescribing orforglipron should: (1) counsel patients about expected GI side effects during dose escalation, (2) follow the recommended dose-titration schedule to minimize GI intolerance, (3) monitor for signs of pancreatitis and discontinue if suspected, (4) assess hepatic and renal function at baseline and periodically, (5) screen for personal or family history of MTC or MEN 2, and (6) review concomitant medications for potential CYP3A-mediated drug interactions
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