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Touted as game-changers for weight loss, drugs like Ozempic, Wegovy, Mounjaro and Zepbound are getting attention far beyond diabetes care

STEP-1 is the largest trial to date and involved 1961 overweight and obese nondiabetics

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At its highest dose, tirzepatide achieves approximately 20-22% weight loss

Below are the most significant trials shaping current prescribing