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These compounds work by mimicking the action of ghrelin, a natural hormone that triggers GH release
Early Clinical Evidence (Small but Promising) A 2025 case series followed five women with lipedema and insulin resistance treated with the GLP-1 medication exenatide (Patton et al., 2025)
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In fact, the World Anti-Doping Agency (WADA) temporarily included it on the list of prohibited substances in 2022 due to its increasing use among athletes to accelerate injury recovery
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While no human studies have yet confirmed these effects, the authors emphasize the need for clinical trials to investigate the potential risks
