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Results In multivariate analysis including the IPSS-R and other key potential prognostic factors, a higher score in the fatigue scale of the EORTC QLQ-C30 was independently associated with overall survival (OS)
Acknowledging the assumptions and potential limitations of the framework, we encourage researchers and statisticians to utilize it and decision makers to be sensitive when subgroup analyses on post-baseline factors are presented for causal inference purposes
Gratzl, K
This triple mechanism distinguishes retatrutide from existing approved therapies such as semaglutide (a GLP-1 agonist) and tirzepatide (a dual GLP-1/GIP agonist)
Potency testing should confirm the stated amount of semaglutide is present (typically within 90-110% of label claim)
CrossRef Distinct tumor immune microenvironment modulation by anti-PD-1/PD-L1, VEGF, and CTLA-4 blockade provides a rationale for triplet therapy in hepatocellular carcinoma Hideki Iwamoto, Hironori Koga, Takumi Kawaguchi Clinical and Molecular Hepatology .2026
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