A retrospective imaging study of 20 patients at Vanderbilt University Medical Center, published in OtolaryngologyHead and Neck Surgery , reported a median 9.0% decrease in total midfacial volume and a rate of roughly 7% of midface volume lost per 10 kilograms of total weight loss
Only 0.61% of cells were duplicated more than ten times and those were entirely due to populations with a substantial difference in the number of cells present in the scRNA-seq dataset versus Xenium dataset
This, in turn, compromises efficacy and limits long-term adherence
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