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Other neoplasias frequently observed in neurofibromatosis type 1 patients include pilocytic astrocytomas, gastrointestinal stromal tumors, pheochromocytomas, and juvenile myelomonocytic leukemia[102]

Cell Metabolism, 34(3), 396-407.e6

Other culprits include intestinal parasites or bacterial overgrowth

For example, these injections increased the amounts of Akkermansia muciniphila , a species known to be more present in the gut when an individual loses weight and in lean individuals

Another study focused on individuals with obesity who did not have diabetes

The headline On Thursday 21 May 2026, Eli Lilly announced that participants in TRIUMPH-1, the first Phase 3 trial of retatrutide in obesity, lost an average of 28.3% of their body weight at 80 weeks on the 12 mg dose, with 45.3% losing at least 30% of their starting weight [1]