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This dual mechanism helps regulate blood sugar levels, preventing hyperglycemia and reducing the risk of diabetes-related complications

Appetite suppression remains the primary ongoing effect, which is the desired therapeutic outcome

The SURMOUNT trial program involved large, diverse populations

303 Interestingly, intracerebroventricular administration of GLP-1 did not inhibit feeding in GLP-1R knockout mice but did in wild-type mice, suggesting that GLP-1R signalling mediates satiety, although no evidence for abnormal body weight or feeding behaviour was reported in GLP-1R knockout mice

Furthermore, the delay in gastric emptying, a key effect of GLP-1 RAs drugs, could contribute further to this effect [58]

The injection went in on time, you didn't do anything different, and yet the number has parked itself