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Health Canada itself has noted that semaglutide is a complex synthetic peptide whose generic versions must demonstrate equivalence in safety, efficacy and quality without any differences that could affect those parameters a bar that has slowed the broader competitive field

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Prioritize adequate protein intake (1.0-1.5 g/kg daily), maintain hydration with 64-80 ounces of fluid daily, avoid dropping below 1000-1200 calories without medical supervision, and engage in regular physical activity