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How should clinicians apply opioid prescribing guidelines when treating acute pain

The dose can be increased to 1 mg or 2 mg weekly if needed for improved glycaemic control

Pain is a common symptom after office-based treatments, and bleeding may also occur

UV exposure is not the root cause - the hormonal state creates the susceptibility - but UV is the primary trigger that activates it

Journal of Clinical Investigation, March 2025

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