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Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency

doi:10.1152/japplphysiol.00945.2010

10.1038/s41598-022-26915-3 505 ZhanX.StamovaB.JinL.-W.DeCarliC.PhinneyB.SharpF

Shippy.

A., de Groot, M

Because of the substantial amounts of brain glutathione and its rapid turnover under homeostatic control, we hypothesized that glutathione is a relevant reservoir of glutamate, and could influence synaptic excitability