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The results were striking: one patient lost only 8.7% of total weight as lean tissue, while the other two actually increased lean soft tissue while losing 26-33% of total body weight

Conclusions Despite advancements in our understanding of DN, addressing the growing healthcare burden posed by this complication of diabetes remains challenging

This oxidative burden results in lipid peroxidation, DNA damage, and hepatocyte apoptosis [127, 128]

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