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Tirzepatide mimics the GIP pathway in addition to the GLP-1 pathway

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Morning of shot: Yogurt, egg, cottage cheese, protein shake

10.1016/j.freeradbiomed.2018.09.014 129 ShaW.HuF.XiY.ChuY.BuS

did not directly point out the treatment potential of GLP-1R agonists for DPN, these results may support the peripheral neuroprotective effect of GLP-1R agonists considering the close association of DPN with adverse limb events (60)

For one-step reactions, all components were mixed in 96-well microtitre plates in 100 l volume (PS, F-Bottom, clear, Greiner) and reactions were performed for 30 min in a Spark 20 M (Tecan) plate reader at 30 C