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This would have a tremendous impact on mood

According to the UK SmPC, these include: Nausea (very common, affecting more than 1 in 10 patients) Diarrhoea and constipation (very common) Vomiting and abdominal pain (common) Decreased appetite and dyspepsia (common) These symptoms are generally mild to moderate in severity and tend to diminish over time as the body adjusts to the medication

Fatigue or a sense of reduced energy is another common experience during the first 24 hours

Looking ahead, the most noticeable effects are likely to be higher prices, increased drug shortages, and reduced access for patientsespecially for generics and high-demand specialty drugs

Smoking significantly exacerbates this risk, with recent evidence showing that cigarette smoking is associated with a 22% increased risk of CVD events in MASLD patients compared to non-smokers (aHR 1.22, 95% CI 1.151.30) [71]

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