Skin irritation tests completed, making it safe to use for sensitive and acne-prone skin types
The approval was granted based on data that showed the drugs effectiveness against antimicrobial resistance in gram-negative bacteria, especially resistance mediated by both extended spectrum beta lactamases and AmpC, according to Allecras announcement
Available online at: 129 WyllieS.ThomasM.PattersonS.CrouchS.De RyckerM.LoweR.et al (2018)
Freezing the vial destroys it, and letting it warm above 10C accelerates degradation
CooperHEKadenEHallidayLFBamiouDEMankadKPetersCet al
Finally, through controlled-release mechanisms, these materials maintain effective bactericidal concentrations at the infection site, preventing exposure to sublethal doses and thereby suppressing the enrichment of drug-resistant mutants