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[1] For example, if a 2 mL dose (full 200 mg thiamine, 200 mg niacinamide) is to be given IV, a nurse might mix it into 50 mL of saline and infuse over 15-30 minutes

Subcutaneous injections are administered under the skin into fat between the skin and muscle

For this reason, it is not uncommon to feel tired and sluggish when vitamin B12 stores are low