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With aging, muscle stem cell function gradually declines, showing reduced proliferation and fusion, leading to impaired regeneration-one of the key mechanisms underlying sarcopenia.In vitro experiments confirm that 5-amino-1mq significantly enhances the proliferation and fusion of muscle stem cells from aged mice

It allows for a quantitative BBBP assessment both in healthy and diseased vessels with an adequate spatial resolution

Comparative analysis showed that D-CuP exhibited higher binding affinities than its monomeric counterpart M-CuP, with Vina scores of -5.7 kcal/mol for p53 and -6.4 kcal/mol for HDAC7, compared to -4.2 kcal/mol and -4.8 kcal/mol for M-CuP, respectively (Fig

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10.3389/fragi.2023.1148926 71 GarmanyA.YamadaS.TerzicA

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