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Although the pathogenesis of preeclampsia has yet to be determined, placental ischemia/hypoxia is regarded as an important contributor through the induction of OS, which in turn can trigger the endothelial cell dysfunction characteristic of the disease

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The choice usually comes down to whether independent dose control matters more than convenience

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70 , e50 (2019)

DOI: 10.1371/journal.pone.0035054 9