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Institutional review board statement The study was conducted in accordance with the guidelines of the Declaration of Helsinki and approved by the Institutional Review Board of Tohoku University Graduate School of Medicine (20221 - 847, 20241 - 184)

Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity

doi: 10.1210/en.2006-0453

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Do not use if you or a family member has ever had medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) because tirzepatide may increase thyroid tumor risk