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Common Adverse Effects of GLP-1s The most common adverse effects of GLP-1 receptor antagonists 26 are gastrointestinal-related, including: Nausea Diarrhea Vomiting Constipation Abdominal pain Dyspepsia/indigestion (upset stomach) Nausea is the most common of the GI symptoms, affecting up to 50% of users, but the frequency often gradually reduces as therapy continues
Sleep 19 , 205213 (1996)
Was it more uncomfortable than expected
Look for patterns in protein intake, meal frequency, problematic foods, and correlation between eating patterns and side effects
Native GLP-1 is rapidly degraded by dipeptidyl peptidase-4 (DPP-4), resulting in a short plasma half-life of approximately 12 min [11]
Follow the recommended dosage instructions provided on the product label
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