The outer layer of the skin, Stratum Corneum, is around 1020 m (very thin), but it is the main barrier for drug penetration
However, researchers have compared the impact of both drugs from different studies and suggested that the higher doses (10mg and 15mg) of tirzepatide might reduce weight by 5.15kg more than 2mg of semaglutide
Another point to consider is that more weight loss is not necessarily better
When you take a GLP-1 medication like semaglutide (Wegovy, Ozempic) or liraglutide (Saxenda), it: Slows down how quickly food leaves your stomach, which keeps you feeling full for longer Signals to your brain that youre satisfied, reducing those constant thoughts about food and snacking Helps your pancreas release the right amount of insulin when your blood sugar rises These medications were initially developed for type 2 diabetes, which is why you might have heard of Ozempic being used off-label for weight loss
Semaglutide side effects primarily involve the gastrointestinal system
Women who are pregnant or nursing and individuals with health conditions or on medications should be especially careful before using the supplement