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Given the emerging role for ferroptosis in antitumor immunity, we tested lipophilic statins including simvastatin alone and in combination with -PD1 in vivo and found that simvastatin and -PD1 promoted tumor clearance and extended survival in 20% to 60% of mice alone but in nearly 100% of mice when administered together
More importantly, the cytotoxicity of MSN-ss-SA and free SA was further evaluated in human hepatocyte L02 cells (Figs
Gastroenterology 150 , 194205 (2016)
Multiple peptides exert their brain repair effects primarily through BDNF elevation, including Semax, Selank, and PE-22-28