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(3) Clinical translation: while certain clinical drugs can induce cell death through ROS, the exact extent of the anti-cancer effects of these drugs has not been determined

For example, Gros et al

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These findings are mechanistically coherent with GHK-Cus anti-inflammatory NF-kB activity because the secondary injury cascade in SCI involves microglial activation, sustained pro-inflammatory cytokine release, and reactive oxygen species generation

The peptide does not interact with hormonal pathways, making it one of the few compounds where sex-based dose adjustment is unnecessary

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