Gupta, V
NRF2 is tightly regulated at different levels by epigenetic modifications such as OS, inflammation, and different forms of stress [148], and has regulatory functions in mitochondrial biogenesis and cellular energy metabolism [149]
Principal Investigator of this study and supervised this study: CC
This means that working on cancer cells alone will not achieve the goal of completely eliminating the tumor and new treatment strategies should consider the TME, that is, the surrounding immune cell components
In conclusion, natural remedies provide a multi-target strategy for chronic, symptomatic illnesses including dry eye disease (DED), while current medications are frequently curative
Alpha-tocopherol (major form of vitamin E in our body) is oxidized, forming an alpha-tocopherol radical