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While the observed associations do not establish causality, they highlight the importance of vigilance for potential NAEs during treatment, particularly given the heterogeneous temporal patterns of onset across events

Endocrine Connections, 6 (8), 647-658

[ Randomized controlled trial, general recommendation ] Key question Is the use of GLP-1 RAs more effective than basal insulin in improving health outcomes for people requiring strong glucose-lowering therapy

10.1006/bbrc.1999.0521 99 VaupelP.HckelM.MayerA

Review of the dermorphin family: selective mu-opioid agonists, potent analgesics in rodents and primates, some able to cross the blood-brain barrier after peripheral dosing, with reports of less tolerance/dependence than morphine in animal studies

Uptake of weight-loss drugs also helped boost like-for-like store sales by 5.8% and overall revenue 3.2% to 7.5bn