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Description

Multiple gut-liver axis abnormalities in children with obesity with and without hepatic involvement

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In the clinical study,Sinetrolshowed a meaningful decrease in abdominal fat and reduction of waist and hip circumference compared to the placebo control group

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The mechanisms through which Vit.E suppresses NF-B activation likely pertain to its antioxidative properties

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Cohort = dose arm within a single trial

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The medication is administered via subcutaneous injection, typically once weekly, using prefilled disposable pens

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