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When clinically appropriate, providers may prescribe tirzepatide (Zepbound, Mounjaro), a GLP-1/GIP medication, or semaglutide (Ozempic, Wegovy), a GLP-1 medication
This puts tesofensine in the same effectiveness range as modern weight loss peptides , but unlike semaglutide's gradual appetite suppression , tesofensine works through metabolic acceleration and dopamine-mediated satiety changes
At 500 mcg per day with a consistent caloric deficit, responders may see 1-2 inches of waist circumference reduction
However, research suggests they may be associated with certain eye-related risks in some patients
FAQ Is retatrutide approved yet
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