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9, sidG is transcriptionally up-regulated during iron starvation, as previously shown 34 , and down-regulated in egtA , yap1 and nearly undetectable in egtA yap1

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GLP-1 RA exenatide alleviated the polycystic ovarian morphology in rats with PCOS, semaglutide treatment not only alleviated PCOS phenotypes but also reversed ovarian ferroptosis markers, restored GPX4 expression, and reduced the GPX4 promoter hypermethylation and DNMTs levels, with efficacy comparable to 5-azacytidine

TGF-: the master regulator of fibrosis