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However, this study failed to show a benefit of OCA in NASH resolution without fibrosis progression

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Will a Vitamin B12 injection interfere with my medications

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Studies demonstrating efficacy used 25mg daily, though some practitioners start patients at 12.5mg for the first two weeks to assess tolerance

Between group differences in secondary and exploratory outcomes will be assessed using regression models as appropriate to the response outcome distribution using baseline values of the respective outcomes as adjustment covariates