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Skipping this step is the fastest way to introduce contamination into your solution

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A hybrid helix containing both deoxyribose and ribose polynucleotides and its relation to the transfer of information between the nucleic acids

Neuman MG, Shear NH, Malkiewicz IM, Kessas M, Lee AW, Cohen L

A noteworthy investigation found that those alterations particularly occurred in mitochondria and resulted in mitochondrial dysfunction