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In vitro research has demonstrated that the flavonoids such as castidin, quercetagetin, and isovitexin have an effect on oestrogen receptors (95)

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[3] Dosing follows a monthly escalation schedule designed to minimize GI side effects: 0.8 mg 2.5 mg 5.5 mg 9 mg 14.5 mg 17.2 mg, with the target maintenance dose reached after about six months