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Notably, in erythroid cells, caspase-3 activation does not guarantee apoptosis execution, since the transcriptional factor GATA-1 essential for erythropoiesis is protected from caspase-3 by HSP70 (heat shock protein 70)

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This is consistent with previous reports showing upregulation of genes responsible for amino acid catabolism, specifically D-serine deaminase ( dsdA ) when UPEC were grown in human urine 37,39

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Rationale and clinical data supporting nutritional intervention in Alzheimer's disease

5.4.2 Effects on liver Despite the lack of expression of GIPR (41, 191) and GLP-1R (192, 193) in hepatocytes, both GIP and GLP-1 have indirect effects on hepatic lipid and glucose metabolism (194)