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In contrast to small-molecule compounds, peptide drugs demonstrate pharmacokinetic characteristics of short elimination half-life and poor metabolic stability in vivo

Emerging approaches, such as antioxidants, NMDA receptor modulators, and cognitive rehabilitation, show promise but require further validation

Heme oxygenase-1 modulates ferroptosis by fine-tuning levels of intracellular iron and reactive oxygen species of macrophages in response to Bacillus Calmette-Guerin infection