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Bejarano I, Monllor F, Marchena AM, et al

4 Immunosuppressive drugs or disease may dull the suppression of parasite division by the host immune system and allow the slowly dividing bradyzoites in tissue cysts to begin rapid division, thereby reactivating the infection with tachyzoites

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Most UA is filtered from glomerular, while renal tubules reabsorption and secretion regulate the amount of urate excretion (Jessica Maiuolo et al., 2016)