This susceptibility is especially pronounced in diabetes, where oxidative stress is heightened, and antioxidant enzyme activity is reduced
Tailor P, Raman T, Garaganta CL, Njalsson R, Carlsson K, Ristoff E, Carey HB: Recurrent high anion gap metabolic acidosis secondary to 5-oxoproline (pyroglutamic acid)
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Demirci T, Gedikli S, Ozturk N, Celep NA (2019) The protective effect of N-acetylcysteine against methotrexate-induced hepatotoxicity in rat