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Another frequent issue is injection site reactions

Now we know that Saxenda and Victoza use the same active ingredient, which works the same way no matter what youre using it for so why are they used for different things

Results announced in September 2025 and published in The Lancet in February 2026 demonstrated orforglipron's superiority over oral semaglutide on both HbA1c reduction (approximately 2.2 vs 1.4 percentage points) and weight loss (approximately 9.2% vs 5.3%)

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Weight loss plateaus are common as the body adapts to reduced calorie intake and lower body weight