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It binds copper(II) with high affinity (association constant in the range of 10 to the power of 16 per molar, placing it among the tighter biological copper chelators)

The excitement around BPC-157 for nerve-related issues like sciatica stems from several of its observed mechanisms of action in animal and in-vitro studies: Angiogenesis: It has been shown to promote the formation of new blood vessels

Long-term safety data, including cardiovascular outcomes, will be essential before widespread clinical use

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Most patients report significant improvement within 4 to 8 weeks as their bodies develop tolerance