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"Peptide bioregulators: a new class of geroprotectors." Bulletin of Experimental Biology and Medicine , 133(2), 115-119

Kim, J., An, Y

Stone, T

Nasal mucosal epithelial cells demonstrated reduced apoptotic marker expression including cleaved-CASP-3, cyt-c, NLRP3, ASC, IL-1, IL-18, CASP-1, and cleaved CASP-1, and increased Bcl-2, confirmed by TUNEL-positive apoptotic cell reduction, suggesting an inhibition of anti-apoptotic and anti-inflammatory effects on nasal tissue [219]

The suppositories are removed from the mold by the patient peeling the two halves of the mold apart from the bottom