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If you experience side effects at any dose level, your provider may hold at that dose for an additional 4 weeks before increasing

In a 48-week phase 2 trial published in The New England Journal of Medicine , adults with obesity (without type 2 diabetes) receiving once-weekly subcutaneous retatrutide at the 12 mg amount achieved a least-squares mean body weight reduction of 24.2%, compared with 2.1% in the placebo group [1]

Retatrutide stands out because it affects three hormone receptors at once: GLP-1, GIP, and glucagon

Weight reductions of 5% or more, 10% or more, and 15% or more were observed in a high proportion of Retatrutide recipients

Metabolic Impact Retatrutide improves the bodys ability to utilize glucose, allowing it to maintain better blood sugar control even in those without diabetes

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