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The Canadian Peptide Research Society is one organization helping advance peptide science in Canada through: research collaboration education and training scientific conferences and knowledge sharing exploration of emerging clinical applications You can learn more about their work here: Current research efforts in Canada and internationally are focused on: developing peptide-based medications (e.g., metabolic and hormone therapies) understanding how peptides influence tissue repair and inflammation advancing drug discovery and personalized medicine However, in musculoskeletal medicine specifically: most research remains preclinical (animal and laboratory studies) high-quality human clinical trials are still limited What this means for patients: Peptide research is an active and evolving field, and Canada is contributing to its development
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Animal experiments confirmed that dural injection of bone marrow mesenchymal stem cell-derived exosomes miR-367-3p significantly reduced the expression of EZH2 in spinal cord tissues of EAE mice, increased the expression of SLC7A11, GPX4, GSH, and SOD, decreased the levels of Fe 2+ and MDA, inhibited spinal cord iron deposition, ferroptosis, and inflammation, and alleviated spinal cord injury ( 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue
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