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Our results indicate that the survival benefits and renoprotective effects of GLP-1 RAs remain consistent regardless of the concurrent use of other anti-diabetic agents or RAAS blockers

Kalsbeek, A., Fliers, E., Hofman, M

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In vivo, Ex-4 has been demonstrated to inhibit prostate cancer cell growth by activating GLP-1R, reducing s-phase kinase-associated protein-2 (SKP2) gene expression, subsequently increasing p27Kip1 (p27) protein levels, and inducing tumor cell cycle arrest [67]