This might lead to the accumulation of acetyl-CoA and NADH (Adeva-Andany et al., 2019), thereby inhibiting -oxidation and preventing fatty acid oxidation in cardiomyocytes
GLP-1 weight loss injections, including options like semaglutide and tirzepatide, can support your weight loss goals by helping you feel fuller, reducing appetite, and making it easier to follow a nutrition plan
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And yet, its still one of the most misunderstood.In this episode, Im joined by exercise scientist and researcher Derrick Van Every , author of the 2025 review Load-Induced Human Skeletal Muscle Hypertrophy: Mechanisms, Myths, and Misconceptions , to separate what actually drives muscle growth from what simply shows up alongside hard training.Together, we break down the human evidence, challenge long-standing myths, and clarify how lifters and coaches should actually approach hypertrophy-focused training.In this episode, we cover:MECHANICAL TENSION AS THE PRIMARY DRIVER OF HYPERTROPHYWHAT ROLE IF ANY DOES METABOLIC STRESS PLAY IN MUSCLE GROWTHDOES THE PUMP CONTRIBUTE TO MUSCLE GROWTH?DO ACUTE CHANGES IN HORMONES FROM TRAINING INFLUENCE HYPERTROPHY OUTCOMESHOW SHOULD WE APPROACH TRAINING TO MAXIMIZE MUSCLE HYPERTROPHY?If you want a clear, evidence-based understanding of how muscle is actually built and how to structure your training around the variables that matter most, this conversation will bring clarity.WHERE TO CONNECT WITH ME:Follow Brandon on IG: Info on Brandons Coaching Services: [email protected] Brandons Website: METABOLIC & PHYSIOLOGIC FLEXIBILITY: BUILDING A BODY THAT ADAPTS WITH DR

Animal data covers relatively short treatment cycles, and extrapolating beyond that requires clinical judgment