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The discrepancies between our findings and those of previous reports may be attributed to differences in disease pathology and cell type-specific responses

In a large meta-analysis examining 16,485 patients, colitis and hypophysitis were more frequent with ipilimumab, while diabetes and pneumonitis were more frequent with anti-PD-1/PD-L1 (35)

Emerging evidence positions ferroptosisan iron-dependent cell death driven by iron-catalyzed peroxidation of esterified polyunsaturated fatty acids (PUFAs) in membrane phospholipidsas a pivotal mediator of COPD pathogenesis

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Consistent with the transcriptomic prediction, the GLP-1R agonist (GLP-1RA) exendin-4 (0.1,1, and 2 g/kg body weight) reduced food intake in both WT and Bbs5 / fasted mice (Figure 4, K and L) in a dose-dependent manner (Figure 4, M and N)