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Excessive melanin production leads to hyperpigmentation, such as melasma and dark spots

114 The absence of the GSTT1 enzyme is identified as an independent, strong predictor of premature vascular morbidity and mortality among individuals with type 2 diabetes

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Human clinical trials are limited, and regulatory status varies by jurisdiction

These may include injection site discomfort or mild swelling, occasional headache, or mild fatigue, particularly with appropriate dosing and patient preparation including adequate hydration

Liao Q, Deng J, Tong J, Gan Y, Hong W, Dong H