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Most of the guidance available comes from understanding each medication's individual cardiovascular profile and applying general pharmacological principles

However, many lines of evidence indicate neuronal sensitivity to oxidative damage

This review highlights tirzepatide, a novel dual agonist of GLP-1 and GIP receptors, which has demonstrated significant improvements in glycemic control, weight loss, and potential cardiovascular and renal benefits, marking it as a promising advancement in T2D treatment

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HbA1c: a review of non-glycaemic variables