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While the Cmax values observed on the first day for all hydrogel-based TZP and Sema formulations might be expected to cause nausea and suppressed food intake in rodents, no changes to animal behavior were observed throughout the study

Am J Physiol Heart circulatory Physiol (2009) 296(4):H110816

If you also experience vomiting, severe abdominal pain, or signs of dehydration (dry mouth, dark urine, dizziness), contact your healthcare provider immediately

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Medical Supervision Physician guided care is one of the most important factors influencing how smoothly and effectively semaglutide works