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TGF-1 plays a role in the late stages of prostate cancer, aiding the potential of cell invasion [19]

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In addition, apigenin modulates the Th1/Th2 balance by suppressing Th2 responses (IgE, histamine, ILs, GATA3, Signal transducer and activator of transcription 6 (STAT6), Suppressor of cytokine signaling-1 (SOCS1), and NF-B) ( 3.2.2 Baicalin Baicalin is the main glycosyloxyflavone of Scutellaria baicalensis Georgi [Lamiaceae]

The result could further be an indication of a substantial and rising off-label prescribing of GLP-1 RAs, something which aligns with previous indications of an increasing off-label prescribing and misuse of GLP-1 RAs [28,29,30,31, 60], together with a media picture of substantial misuse which has been reported in recent years [23, 26, 27, 34, 36, 68]