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It also switches melanin production from eumelanin (brown or black) to pheomelanin (yellow to red)

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FIGURE 1 3.2 Daphnetin attenuated oxidative stress of diabetes cognitive dysfunction rats As shown in Figure 2, STZ-treated caused oxidative stress in rat brain, which increased the MDA content and GSSH content, and reduced the levels of SOD, CAT, GSH, Gpx and TAC, while daphnetin-treated inhibited these changes in oxidative stress-related medicators, which indicated that daphnetin could mitigate oxidative stress of diabetes cognitive dysfunction rats

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[DOI] [PubMed] [Google Scholar] 143.Di Simplicio P., Cacace M.G., Lusini L., Giannerini F., Giustarini D., Rossi R