Finally, many published studies are associative and cross-sectional, which limits causal inference
MM: Conceptualization, Writing review & editing, Supervision
Dysfunctional mitochondria in neutrophils, macrophages, and T lymphocytes alter cytokine production, phagocytic activity, and antigen presentation, tipping the balance toward excessive inflammation or postoperative immunosuppression, thereby exacerbating organ injury
Dietary meat restriction attenuates carnitine-to-TMAO conversion, suggesting that TMAO production may not occur in meat-restricted individuals taking supplemental l-carnitine, but this has not been tested
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling
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