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Pregnancy and breastfeeding: There is insufficient safety data for peptide use during pregnancy or lactation

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A network-based analysis of systemic inflammation in humans

Results: HH exposure led to pathological changes in hippocampal tissue, accompanied by increased oxidative stress, inflammatory response, and BBB disruption, and then induced impaired cognitive function in mice

Addressing these neurological changes requires interventions capable of modulating neural function, not just blocking peripheral pain signals