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A small Phase 1 study measured tirzepatide in breast milk samples and did not detect the drug in those samples

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The latter Cochrane review reported that AOX supplementation in infertile men resulted in a significant increase of CPR (odds ratio (OR) 2.97, 95% confidence interval (CI) 1.91-4.63) although the level of evidence was found to be low (100)

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Thyroid function tests (TSH and free T4) should be checked if significant weight change occurs or symptoms of thyroid dysfunction develop